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Country Profile on the Netherlands While many countries have shifted in rank from the previous year, the Netherlands maintains its position as the 4th most competitive global economy in the 2017-2018 report. This comes as a result of top scores across three WEF subindexes, including top 10 ranks for institutions, infrastructure, health and primary education, higher education and training, goods market efficiency, technological readiness, business sophistication and innovation. The Netherlands scores especially high on the quality of its port infrastructure (#1), quality of air transport infrastructure (#4), quality of scientific research institutions (#4) and university-industry collaboration in R&D (#5). The Global Competitiveness Report in 2017 WEF published its latest Global Competitiveness Report on September 26, 2017. Released annually, the report is a comprehensive assessment of the factors driving productivity and prosperity in 137 economies. For the ninth consecutive year, Switzerland ranks as the world’s most competitive economy, ahead of the United States and Singapore. The Netherlands and Germany make up the remaining top five spots. The Netherlands previously climbed four places in two years before sustaining its current position. Hong Kong SAR (#6) advanced three places, while Sweden (#7) dropped one place from last year. Of the remaining three economies in the top ten, the United Kingdom (#8) and Japan (#9) each fell one place. Finland (#10) remains consistent. Source: World Economic Forum Global Competitiveness Report 2017-2018

The Netherlands maintains its prominent position thanks to the support of a strong education system and high levels of tech readiness among businesses and individuals. Its innovation ecosystem is ranked 6th globally, putting Holland in an excellent position to develop new ideas and attract investment.

World Economic Forum The Global Competitiveness Report 2017-2018

Country Profile on the Netherlands

While many countries have shifted in rank from the previous year, the Netherlands maintains its position as the 4th most competitive global economy in the 2017-2018 report. This comes as a result of top scores across three WEF subindexes, including top 10 ranks for institutions, infrastructure, health and primary education, higher education and training, goods market efficiency, technological readiness, business sophistication and innovation. The Netherlands scores especially high on the quality of its port infrastructure (#1), quality of air transport infrastructure (#4), quality of scientific research institutions (#4) and university-industry collaboration in R&D (#5).

The Global Competitiveness Report in 2017

WEF published its latest Global Competitiveness Report on September 26, 2017. Released annually, the report is a comprehensive assessment of the factors driving productivity and prosperity in 137 economies.

For the ninth consecutive year, Switzerland ranks as the world’s most competitive economy, ahead of the United States and Singapore. The Netherlands and Germany make up the remaining top five spots. The Netherlands previously climbed four places in two years before sustaining its current position. Hong Kong SAR (#6) advanced three places, while Sweden (#7) dropped one place from last year. Of the remaining three economies in the top ten, the United Kingdom (#8) and Japan (#9) each fell one place. Finland (#10) remains consistent.

Source / World Economic Forum

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European Headquarters in The Hague for Indian cyber security firm E2Labs

From left to right: Richard Franken (HSD), Karsten Klein (Deputy Major of The Hague), Dr. Zaki (Chairman & CEO E2Labs), Venu Rajamony (Ambassador of India) and Chris van Voorden (InnovationQuarter) © Daniel Verkijk

Official training in ethical hacking

E2labs offers ethical hacking training, cyber security training, career oriented programs, licensed ethical hacking and advanced diploma in computer hardware & networking. In India, E2Labs is partnering with the Government of India to help meet the talent shortfall of 2 million skilled cyber security professionals.

As an information security training specialist with the distinction of establishing Asia’s 1st Anti Hacking Lab+Academy at Hyderabad, E2Labs is helping bridge the talent gap as it trains scores of candidates to deliver a perennial pipeline of qualified talent for the global information security industry.

E2Labs received distinctive awards for its services. They’re one of the Top 20 Most Promising Cyber Security Companies of India, are positioned in the Top 100 Companies of Asia (Red Herring, US) and are Highly Appreciated by W.I.P.O (United Nations). Recently, E2 Labs was handpicked to be the exclusive training partner in India for Mile2, world’s largest certification body for information security.

European Headquarters in The Hague for Indian cyber security firm E2Labs

Bridging the IT talent gap

E2Labs aims to leverage The Hague’s knowledge and expertise in cyber security, forensics, national security, and critical infrastructure to drive capacity building through a range of skill development programs to be imparted across the country. E2Labs seeks to utilize The Hague Security Delta’s (HSD) profound insights and the access to latest innovation to create globally-relevant, outcome-driven training programs in the security domain that lead to the creation of highly skilled IT professionals for the global cyber security industry.

Sharing the collective mission of HSD, E2Labs seeks to partner pro-actively with knowledge institutions, governments, businesses, the ‘triple helix’, to help enable more jobs and create a safer and more secure world.

European Headquarters in The Hague for Indian cyber security firm E2Labs

European Headquarters based in The Hague

Deputy Mayor Karsten Klein is The Hague’s alderman for Economic Affairs, Harbours, Welfare and Health and met E2Labs’ Dr. Zaki for the first time in October 2015 during an economic mission to India. A delegation consisting of Dutch companies, HSD partners and government visited the Hyderabad region to learn about the developments in India and the economic development that the 1.3 billion people nation is undergoing. Rinke Zonneveld, InnovationQuarter’s director, joined this mission where the European expansion plans for E2Labs were discussed.

Succeeding the mission, and with the Data Security Council of India (DSCI) and the National Association of Software and Services Companies (NASSCOM), Dr. Zaki visited the City of The Hague and The Hague Security Delta several times over the past two years. In 2016 preparations were made to establish the company in the Netherlands and now, during the Cyber Security Week 2017 in The Hague, the opening of E2Labs European headquarters is officially celebrated.

We at E2Labs consider it a privilege to be associated with the world’s largest cyber security community, The Hague. This is a major boost to our company and will help advance our capabilities in IT security to impart improved training programs, enable us provide enhanced security assistance to governments and aid in delivering high performance consultancy services to our roster of 400 clients spread across the globe.
~Dr. Zaki, Chairman & CEO of E2Labs

“In its search for a suitable location for their European Headquarters, E2Labs was well supported by InnovationQuarter in co-operation with The Netherlands Foreign Investment Agency (NFIA), HSD and the City of The Hague,” says Chris van Voorden, Director Foreign Investments at InnovationQuarter. “We are pleased with the choice of E2Labs for The Hague, and are proud to see that they recognize The Hague’s rich cyber security community and the strong innovation culture in The Netherlands.”

European Headquarters in The Hague for Indian cyber security firm E2Labs

Indian delegation with o.a. E2Labs visit the Municipality of The Hague, The Hague Security Delta and the Cyber Security Week © Daniel Verkijk

Strong ties with India

Netherlands and India share strong bilateral ties. Netherlands is India’s 5th largest investment partner and 3rd largest source of foreign direct investments (FDI) globally. Importantly, both countries espouse the same values with respect to laws and security. E2Labs’ presence at The Hague will help strengthen the ties further through co-operation on cyber security, a critical area which has emerged as one of the biggest challenges of today’s society.

To strengthen the bilateral relationship, The Hague and the state of Karnataka have signed a MoU, which actively focusses on startups, cyber security and elderly care technology. The Municipality of The Hague regularly visits Bangalore (the state of Karnataka) to implement the MoU and creates awareness for The Hague as an international city that welcomes Indian entrepreneurs and businesses. Due to the intense focus of the Municipality of The Hague and its acquisition partners such as InnovationQuarter, the establishment of E2Labs in The Hague can be considered a result of this co-operation.

Impact Startup Fest is one of the first results of the partnership between The Hague’s startup programme and the Indian organisation Intellecap, which has forged an international partnership between The Hague, India and Kenya. This partnership offers a springboard for Dutch impact startups to explore the Indian market and vice versa.

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Blockchain platform provider KrypC Technologies opens its European office in The Hague

From left to right: Mark Beermann, Danny Frietman (Enterprise Summit), Karsten Klein (Deputy Major of The Hague), Ravi Jagannathan (MD & CEO KrypC), Venu Rajamony (Ambassador of India), Ilja van Haaren (The Hague Business Agency), Chris van Voorden (InnovationQuarter) and Paul de Kroon (34 Capital)

KrypC’s Enterprise-ready blockchain-based platforms

While being a software technology business ‘by design’, KrypC Technologies’ blockchain-based platforms help public institutions and enterprises across every industry to accelerate their blockchain journey. KrypC works with big enterprises to literally bring the advanced capabilities of blockchain within reach of decision makers, and helps them discover the power and value of blockchain-based applications for business. KrypC also attracts attention from other fast-growing technology and software ventures, which see that KrypC’s platforms and solutions help them get ‘blockchain-ready’ much faster.

The founding team of KrypC Technologies brings considerable technology and operational experience and expertise in the fields of cryptography, security, cloud computing, IoT and blockchain technology. In prior technology ventures, they founded one of the largest certifying authority providers in India, a central bank authorized mobile payments business in India, are holders of multiple patents and have been contributors to various technologies and blockchain protocols in open source.

Mr. Ravi Jagannathan said: “Blockchain is still an emerging technology, but is rapidly becoming ‘enterprise ready’. However, the technology develops so fast, and the breadth and depth of required expertise for real enterprise-ready solutions is so deep, that it becomes increasingly difficult to keep track of developments for most companies and institutions. We solve this problem by putting configurable platforms and solutions in the hands of our clients, which are built on the newest and cutting-edge blockchain protocols and cryptography frameworks.”

Furthermore, Mr. Ravi Jagannathan said: “Our clients want to get from ‘A’ to ‘B’, but for that, they don’t need to build an engine to drive the car. We have already built the car with the engine for them: They can use our products and platforms to quickly and effectively get to where they need to be.”

Blockchain platform provider KrypC Technologies opens its European office in The Hague

Ambassadeur van India, Venu Rajamony, heet de Indiase delegatie met onder meer E2Labs en KrypC van harte welkom in Den Haag. © Daniel Verkijk

Expanding to The Hague

The Netherlands is an early adopter for new technology. Strategically located to serve multiple markets within Europe, and the combination of accessibility and an excellent digital infrastructure, a rich talent pool in the area of cyber security and cryptography are the key reasons why KrypC Technologies has established its European headquarter for sales, marketing and R&D in The Hague. KrypC Technologies currently has 30 staff, 20 of which are based in its R&D-center in Bangalore. The remainder are spread across the US and the Netherlands. KrypC Technologies now plans to grow its physical presences both in San Francisco (US) and The Hague.

During KrypC’s exploratory visits to the Netherlands and The Hague, they received a warm welcome from the Netherlands Foreign Investment Agency (NFIA), The City of The Hague, The Hague Business Agency, InnovationQuarter and many other investors and partners in the region. In particular Dutch tech entrepreneur and resident of The Hague, Danny Frietman from Enterprise Summit, created a warm entrance into the Dutch market and partner ecosystem. He and his business partner Mark Beermann will continue to support the expansion of KrypC Technologies.

I am pleased to see that The Hague and Bangalore value its mutual strengths in the area of emerging technologies and cutting-edge R&D. Both cities and countries have a strong appetite for innovation, and culturally connect well. I compliment KrypC Technologies with their choice for The Hague and congratulate them.
~ Mr. Venu Rajamony (Ambassador of India)

Blockchain platform provider KrypC Technologies opens its European office in The Hague

Ambassadeur van India, Venu Rajamony © Daniel Verkijk

“We highly appreciate the strong innovation culture in The Netherlands, and recognize the particular strengths of the The Hague region in the areas of cyber security, cryptography and blockchain development,” says Mr. Ravi Jagannathan, Founder and CEO of KrypC Technologies. “We are excited to work with the local business community and scientific and governmental institutions, as well as fuel the collaboration between our cryptographic and blockchain domain experts and the rich talent pool in this region. We truly appreciate the welcoming environment and support from the Municipality of The Hague, InnovationQuarter, The Hague Business Agency and many others for their assistance to us in setting up our European office. This is an exciting day for us!”

“High-growth ventures like KrypC Technologies look for access to talent and growth capital. In our meetings and discussions with them, we discovered that there is an excellent match between KrypC’s growth ambitions and talent needs, and the talent pool and access to capital that we can offer in the The Hague region,” says Chris van Voorden, Director Foreign Investments at InnovationQuarter. “We are proud that KrypC Technologies have recognized our welcoming business climate and will assist them to kick-start easily in The Hague, the region that is well known in the global community for its strong local cyber security, cryptography and blockchain capabilities which made it the perfect fit for KrypC Technologies.”

Blockchain platform provider KrypC Technologies opens its European office in The Hague

© Daniel Verkijk

Strong ties with India

The Hague hosts a large Indian diaspora community and has had a good relationship with India for many years. To strengthen this bilateral relationship, The Hague and the state of Karnataka have signed a MoU, which actively focuses on startups, cyber security and elderly care technology. The Municipality of The Hague regularly visits Bangalore (the state of Karnataka) to implement the MoU and creates awareness for The Hague as an international city that welcomes Indian entrepreneurs and businesses. Due to the intense focus of the Municipality of The Hague and its acquisition partners, the establishment of KrypC Technologies in The Hague can be considered a result of this co-operation.

Impact Startup Fest is one of the first results of the partnership between The Hague’s startup programme and the Indian organisation Intellecap, which has forged an international partnership between The Hague, India and Kenya. This partnership offers a springboard for Dutch impact startups to explore the Indian market and vice versa.

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The Hague Security Delta verwelkomt Britse cybersecurityspecialist CyNation

As a warm welcome in The Hague, HSD’s Executive Director Richard Franken and InnovationQuarter’s Chris van Voorden present a special plaque to CyNation’s Chairman Steve Berry and Finn McClain, Sales Director Europe and General Manager Benelux at CyTime. © Daniel Verkijk

Replacing vulnerabilities with capabilities

Organisations across all sectors and sizes are faced with having to manage relentless cyber threats and increasing compliance demands such as the General Data Protection Regulation (GDPR). To manage this, organisations have to address information security in an altogether different manner. CyNation believes that automation will resolve these issues and enhance organisations’ effectiveness and efficiency in dealing with cyber security threats and compliance demands. Their solutions aim at providing on-going visibility and monitoring of an organisation’s cyber security and compliance posture, enabling immediate remediation and instant reporting.

CyNation, securing a connected world. We help organisations improve cyber security and compliance posture.

Operating within the Hague’s security community

The Hague is renowned for its international position as the City of Peace, Justice & Security. It provides CyNation with a prosperous business environment and is a central hub to continental European business. Furthermore, CyNation’s membership with The Hague Security Delta (HSD) positions it at the centre of Europe’s leading security cluster. HSD is a community of companies, government organisations and knowledge institutes, who serve as a new market for foreign companies and as a platform to create new (innovative) initiatives. Home to this cluster is the HSD Campus: the innovation centre for the security industry, with living labs, training facilities, flexible office space and meeting rooms.

The Hague Security Delta verwelkomt Britse cybersecurityspecialist CyNation

From left to right: Philip Meijer (InnovationQuarter), Annemieke Busch (NFIA), Finn McClain (CyNation), Steve Berry (CyNation), Chris van Voorden (InnovationQuarter), Nick Breukelman (Department for International Trade (DIT) The Netherlands – British Embassy The Hague) and Martijn van Hoogenhuijze (InnovationQuarter). © Daniel Verkijk

Steve Berry, Chairman CyNation: “We are delighted and proud to make The Hague Security Delta our first office outside the UK. It will be the cornerstone of our European expansion. We have enjoyed tremendous support and hospitality since we started engaging with InnovationQuarter and The Hague Security Delta some time ago. We look forward to building on this and are delighted to be part of this leading security cluster in Europe.”

Chris van Voorden, Director of Foreign Investments at InnovationQuarter, believes that CyNation complements the existing regional businesses. “The company’s activities in cyber security threats and compliance fit nicely in West Holland’s security ecosystem. Finn McClain and his team will surely benefit from working within HSD’s innovative security community to expand their business across Europe.”

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Ambassadors and Trade Counsellors visit The Hague’s Cyber Security Week

The Hague’s security hub

The visit was organised in close co-operation with TradeCouncellors.nl and InnovationQuarter. Director Marion Verboom of TradeCounsellors, Deputy Mayor Saskia Bruines and Chris van Voorden, Director Foreign Investments at InnovationQuarter, welcomed the Ambassadors at the HSD Campus.

In addition executive director Richard Franken explained how the community of businesses, governments and knowledge institutes work together on innovation and knowledge in the field of safety and security.

Core of the Dutch security cluster is the HSD Campus: the national innovation centre of the Dutch security cluster, with living labs, education and training facilities, flexible office space and meeting rooms. Businesses, governments and knowledge institutions from across the country collaborate to harvest knowledge, and develop products and services that contribute to a safer and more secure world.

Ambassadors and Trade Counsellors visit The Hague’s Cyber Security Week

The Ambassadors and their Trade Counsellors were stimulated to participate more in the Cyber Security Week next year and bring more and more companies over to The Netherlands to exchange knowledge and do business with each other. In addition the ambassadors and trade counsellors joined the seminar ‘Getting to know the Dutch Cyber Security Market’.

Ambassadors and Trade Counsellors visit The Hague’s Cyber Security Week

Cyber Security Week 2017

In the same week as the Europol – INTERPOL Cybercrime Conference and the EC-Council’s Global Cyberlympics final, a unique ‘Cyber Security Week’ is being held at several locations in the City of The Hague. From 25 until 29 September, The Hague is the hotspot for the cyber security community. Over 80 events provide the opportunity to meet key players, discuss the latest developments, share knowledge and to pitch innovative ideas for funding! The Cyber Security Week is powered by The Hague Security Delta, the leading security cluster in Europe.

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Cyber Security Week 2017 van start 980x450px

Cyber Value at Risk

During the opening, Inge Philips, director of Cyber Security at accounting firm Deloitte, presented the first copy of the report Cyber Value at Risk to Maarten Camps, secretary-general of the Dutch Ministry of Economic Affairs. The report reveals that the loss of value suffered by the Dutch economy as a whole due to cyber risks totals 10 billion euros, 1.3% of the GNP. Annual losses suffered by SMEs are estimated at 1 billion euros.

In his presentation, Wim Kuijken, chairman of the HSD board , went on to emphasise the need for government, businesses and knowledge institutions to work together, both nationally and internationally.

This was followed by a panel discussion involving Dick Schoof (National Coordinator Counter Terrorism and Security), Jos Nijhuis (CEO Schiphol and chairman of the Cyber Security Council), André Haspels (director-general Political Affairs, Ministry of Foreign Affairs) and Saskia Bruines (deputy mayor Knowledge Economy, International, Youth and Education from the Municipality of The Hague).

Access to Talent

After the panel discussion, the HackLab Kids started in which a group of primary school children emphasised the Access to Talent theme of this first day of Cyber Security Week.

Deputy mayor Saskia Bruines: “There is a rapidly rising demand for well qualified personnel in the field of cyber security. For that reason, it is also important to teach children digital skills from a very early age. From primary school to university, promoting cyber talent must be high on the agenda.”

Richard Franken, executive director HSD:
“The Cyber Security Week is a great example of how we as a national security cluster and our partners can stimulate cooperation and knowledge exchange. Nationally and internationally. So that together we can contribute to a more secure world and economic growth. ‘Together we secure the future’.”

Cyber Security Week

Cyber Security Week takes place from 25 to 29 September in 17 different locations in The Hague and consists of 80 events in which hundreds of experts in the field of Internet security and cybercrime from the government, industry and science can exchange knowledge, discuss the latest developments and pitch new innovative ideas. Together they will seek innovative solutions to one of the greatest challenges in our modern digital world: how do we guarantee a secure cyber future for ourselves?
The event is expected to attract over 3000 visitors to The Hague.

Participants in Cyber Security Week include Europol, INTERPOL, NATO, representatives from various European security clusters from the UK, Belgium, Germany and France, among others, international City-CIOs & CISOs and many large and small businesses specialising in cyber security.

Important events during Cyber Security Week are the Europol-INTERPOL cybercrime conference and the final of the EC-Council hacking competition Global CyberLympics.

Cyber Security Week is an initiative of The Hague Security Delta, the city of The Hague, InnovationQuarter, The Conference The Hague and accounting firm Deloitte and is organised together with 80 partners.

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StartupFest Europe / CapitalFest 2017

StartupFest Europe

Startups are good for the economy. They take care of innovation and employment. In order to grow, startups include capital, knowledge and customers. That’s why Dutch StartupDelta started in 2016 with StartupFest Europe, a European festival where startups and scale-ups find funding to grow their business, meet launching customers and find inspiration from international topnotch speakers.

StartupFest Europe consists of a main event (CapitalFest) and a number of thematic events spread around The Netherlands. This years theme is ‘Global Challenges, Startup Solutions’. At different times during StartupFest Europe there are speakers and challenges about one of the global challenges.

StartupFest Europe connects startups from all regions and sectors, enabling the Dutch startup potential to be visible to national and international investors ~ Francis Quint, Head of InnovationQuarter Capital

Edible drones

During CapitalFest on September 27th in the Beurs of Berlage, Amsterdam, there will a large series of international top speakers on stage (as keynote speaker or participant in a breakout session). In addition, there is a special video message from Jack Ma, CEO of Alibaba.

Some of the speakers are startup or scale-up with a strong focus on one of the world’s challenges. Like Boyan Slat. He is the founder and CEO of The Ocean Cleanup, the company that develops technological solutions for floating plastic in the oceans. Slat started his business in 2013 when he was 18 years old. The Ocean Cleanup has collected $ 31.5 million in funding.

With its company Windhorse Aerospace Nigel Gifford develops edible drones that can be deployed in disaster areas. The drones can transport a few tens of kilos of aid goods in the future.

The Ocean Cleanup

Innovative translator

Tim Houter and his colleagues develop the solution for fast and safe transportation. Houters team recently became second in the SpaceX Hyperloop competition of Elon Musk. The first tests of the Delft Hyperloop are promising.

Vasco Pedro is the founder and CEO of Unbabel, a Portuguese startup that develops the best translator using both artificial intelligence and “real” people. The goal of Unbabel is to make people worldwide work together better and easier.

Eyewire is the company of Amy Robinson Sterling. Eyewire portrays the human brain through the use of an online game. By solving 3D puzzles, everyone can collaborate on visualizing the human neural network.

100 billion dollars

In addition to these five innovative startups, CapitalFest’s stage includes Deep Nishar, the world’s largest investor. Nishar (former vice president at LinkedIn) is managing director of The Softbank’s Vision Fund; The Vision Fund has invested $ 100 billion. CapitalFest gives two startups the opportunity to pitch their company at Nishar. Besides, all startups visiting CapitalFest get the opportunity to present their business to hundreds of other investors.

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Belgische en Duitse stamcelspecialisten gaan samen-980x450px

Joining forces

Ncardia has secured an additional €4.25M from existing investors, Vesalius Biocapital, SFPI-FPIM and Sambrinvest as a direct result of the merger. Both scientific specialists & business units based in Leiden, the Netherlands, Germany, Belgium and the US are focused on meeting the needs of customers in pharma and biotech sectors and have developed a pipeline of innovative products, services and solutions to position Ncardia as the trusted global leader in hiPSC based cardiac drug discovery & development. Dr. Stefan Braam, Pluriomics co-founder has been appointed CEO while Dr. Heribert Bohlen, Axiogenesis co-founder has been named CSO. Dr. Bernd Fronhoff will become COO.

The combined specialist units will allow our customers to accelerate and improve drug candidate selection, lower costs, and ultimately increase drug development efficiency.

“Establishing Ncardia was a strategic decision” said Stefan Braam CEO. “We are bringing the best of both organisations together – our people, products, services, industry knowledge and expertise to develop and generate more innovative stem cell based products and services to serve our customers at an even higher level than before. Our goal is to be the trusted global leader in the hiPSC drug discovery and development field so that Ncardia is the partner of choice for scientists operating in cardiovascular and neural safety and efficacy projects.”

By joining forces, Ncardia can provide assay solutions in a shorter time-frame which will help to accelerate and improve the discovery & development of efficient and safe drugs. The combined business allows Ncardia to build on over two decades of knowledge, stem cell product R&D and commercialization by Pluriomics and Axiogenesis respectively. It gives Ncardia further opportunities for growth in a rapidly developing marketplace.

Heribert Bohlen CSO added, “Combining the scientific excellence and expertise of Pluriomics and Axiogenesis boosts our R&D capabilities. It allows us to accelerate innovations within the cardiac drug discovery & development areas. He went on to say that “the combined specialist units will allow our customers to accelerate and improve drug candidate selection, lower costs, and ultimately increase drug development efficiency.“

Ncardia has more than 60 employees in Europe and the US. The combined teams will continue to engage with clients to develop and provide customers with a broad portfolio of cardiovascular cell models and services. These services range from disease modelling to cardiovascular drug efficacy screening to cardiac safety assessment and implementing Ncardia’s innovative and proprietary cell types in various screening platforms.

InnovationQuarter invested in Pluriomics, which is a spin-off from Leiden University in 2014

This article appeared first on Business Wire

 

 

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Slangengif leidt bij toeval tot middel om te dun bloed te laten stollen-980x450

To avoid spontaneous stroke or deep vein thrombosis, currently millions of cardiac patients worldwide daily take synthetic factor Xa anticoagulants, such as apixaban, edoxaban or rivaroxaban.  But there is one major disadvantage. As yet there is no agent to stop the effect of these anticoagulants. This is a significant unmet medical need for the many patients experiencing severe (internal) bleeding or requiring emergency surgery. Today, when a patient requires emergency surgery, doctors have to wait for the medication to clear, because patients may otherwise suffer from severe bleeding. Due to the increasing use of factor Xa inhibitors for anti-coagulation, global demand for a compound such as PseudoXa is growing rapidly.

Snake venom

R&D was performed by one of the world’s leading groups in hemostasis and thrombosis at the Leiden University Medical Center (LUMC), led by professor Pieter Reitsma. For the research group a snake venom protein of the most venomous snake in the world, the Australian brown snake, was their source of inspiration. The responsible protein in the snake venom causes blood to clot, but differs from that of a human being. The researchers subsequently identified the part of the snake’s coagulation protein that was different and applied this to the human version.

Pieter Reitsma, Professor emeritus of Molecular and Experimental Medicine at LUMC and CSO of VarmX explains: “The altered human protein did exactly what it had to do: in the laboratory our researchers observed that the protein did cause the blood to coagulate, but did not react to the blood thinners. In this way the effect of blood thinners is bypassed. This is ideal when a patient who takes blood thinners requires emergency surgery.”
“Innovative research into the properties of this snake’s venom provided the scientific basis for the factor Xa reversal agent. This is exemplary of the translation of basic research into a potential life-saving therapy. ”

VarmX

VarmX has exclusively in-licensed the rights to the compound from the LUMC and will continue to collaborate with the LUMC. In June 2017 VarmX raised capital and initiated the product development of PseudoXa, with the aim to bring this innovative therapy to the market after extensive clinical testing.

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StartupDelta

Special Envoy Constantijn van Oranje said today, “I am thankful for the trust that was bestowed upon myself and StartupDelta and I look forward to continuing our work. Innovation and entrepreneurship are absolutely crucial for the Dutch competitive edge. I am confident that we have all the right conditions at present to turn the Netherlands into the most innovative start-up nation in Europe.”

Rinke Zonneveld, Director at InovationQuarter: “On behalf of the West Holland startup hubs, InnovationQuarter is a partner of StartupDelta. We look forward to working with Prince Constantijn and his team to strengthen the startup ecosystem in the region in the coming years, in the Netherlands and internationally.”

StartupFest Europe 2017: Global challenges, Start-up Solutions

Constantijn van Oranje is also spearheading StartupFest Europe. From 25-58 September, across various locations in the Netherlands, StartupFest Europe will take place. The ultimate goal is to connect entrepreneurs, investors and businesses, and bring new innovations to the market.

The central event: CapitalFest takes place on the 27th of September at de Beurs van Berlage in Amsterdam. One on one matchmaking sessions will be set up between startups and over 140 international investors. Also on the agenda, acclaimed speakers such as Dutch Prime Minister Mark Rutte, Boyan Slat (The Ocean Cleanup), Werner Vogels (Amazon), Deep Nishar (MD SoftBank Group), Kees Koolen (EQT) and Slava Rubin (Indiegogo).

Other themes include:

Source / StartupDelta

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National Geographic - This Tiny Country Feeds the World

@ Luca Locatelli

In a potato field near the Netherlands’ border with Belgium, Dutch farmer Jacob van den Borne is seated in the cabin of an immense harvester before an instrument panel worthy of the starship Enterprise.

From his perch 10 feet above the ground, he’s monitoring two drones—a driverless tractor roaming the fields and a quadcopter in the air—that provide detailed readings on soil chemistry, water content, nutrients, and growth, measuring the progress of every plant down to the individual potato. Van den Borne’s production numbers testify to the power of this “precision farming,” as it’s known. The global average yield of potatoes per acre is about nine tons. Van den Borne’s fields reliably produce more than 20.

National Geographic - This Tiny Country Feeds the World

@ Luca Locatelli

That copious output is made all the more remarkable by the other side of the balance sheet: inputs. Almost two decades ago, the Dutch made a national commitment to sustainable agriculture under the rallying cry “Twice as much food using half as many resources.” Since 2000, van den Borne and many of his fellow farmers have reduced dependence on water for key crops by as much as 90 percent. They’ve almost completely eliminated the use of chemical pesticides on plants in greenhouses, and since 2009 Dutch poultry and livestock producers have cut their use of antibiotics by as much as 60 percent.

One more reason to marvel: The Netherlands is a small, densely populated country, with more than 1,300 inhabitants per square mile. It’s bereft of almost every resource long thought to be necessary for large-scale agriculture. Yet it’s the globe’s number two exporter of food as measured by value, second only to the United States, which has 270 times its landmass. How on Earth have the Dutch done it?

This story appears in the September 2017 issue of National Geographic magazine. Read the full article on www.nationalgeographic.com.